Is it possible that increased anxiety and hyperactivity can be an effect of thuja? I gave Blossom a total of 2 doses over 2 days. Today I took her in the car and her anxiety and hyperactivity were increased greatly. Back to square one almost. Car time was greatly reduced and I drove her home.... We were out no more than 10 minutes. We were making progress and now I don't even know if I can get her to the vet wednesday for her xray, to investigate her polycytemia. She is peppier in her walking. The only thing in diet I changed was adding fish oil, curcumin and B vitamins to help hopefully thin her thick blood. I have given my dogs thuja in the past and no problem. I do not know if this heightened anxiety and her peeing last night in the house are related to the thuja. I also noticed she is reactive at times looking behind her as if she thinks something is there. Oh please tell me this is not THAT powerful to create this change. :-(